- Title
- Managing severe tetanus without ventilation support in a resource-limited setting in Bangladesh
- Creator
- Hasnain, Md Golam; Maruf, Shomik; Nath, Proggananda; Anuwarul, Azim; Ahmed, Md Nasir Uddin; Chowdhury, Iqbal Hossain; Basher, Ariful
- Relation
- American Journal of Tropical Medicine and Hygiene Vol. 99, Issue 5, p. 1234-1238
- Publisher Link
- http://dx.doi.org/10.4269/ajtmh.18-0180
- Publisher
- American Society of Tropical Medicine and Hygiene
- Resource Type
- journal article
- Date
- 2018
- Description
- Tetanus, a vaccine-preventable and potentially fatal disease, continues to remain prevalent in low- and middle-income countries. Furthermore, physicians are often unfamiliar with management of severe tetanus without ventilator support. Therefore, we proposed a modified treatment protocol that provides a low-cost and effective solution for the management of severe tetanus in resource-constrained settings. This is an observational study of 42 patients with severe tetanus treated during 2015-2016 at Surya Kanta Hospital, Bangladesh. This facility does not have an intensive care unit (ICU), and patients admitted here were provided treatment with the modified protocol. A total number of 42 patients with severe tetanus were treated with the modified protocol. Among them, 24 (57.1%) recovered completely, six (14.3%) recovered with the sequela, and 12 (28.6%) died. Among those who recovered with the sequela, four needed mechanical support during walking and two had a visual impairment. No significant adverse event was recorded during the treatment period. The results gathered during this case series provide a sustainable, low-cost, and effective solution to management of severe tetanus in resource-constrained settings where ICUs are unavailable.
- Subject
- tetanus; ventilator support; Bangladesh; resource-constrained settings
- Identifier
- http://hdl.handle.net/1959.13/1419918
- Identifier
- uon:37514
- Identifier
- ISSN:0002-9637
- Language
- eng
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